TMSS Medical College Journal

Background: Dengue viral infection is one of the common arboviral infections in tropical and subtropical countries. Haematological examination is an essential step in the management. In few cases it can give clue to the underlying diseases. Early diagnosis of dengue is important for provision of special care which ensure marked reduction of morbidity and mortality. This study was conducted document the haematological changes in Dengue fever. Aims and Objectives: To describe the haematological changes during this evaluation of dengue fever. Materials and Methods: This descriptive cross sectional study was conducted in TMSS Medical College, Bogra and Popular Diagnostic Center Ltd. Bogra during March 2016 to November 2016. It Including 66 cases of dengue and there haematological profile was done. Results: The most common haematological abnormality was thrombocytopenia followed by leucopenia, atypical lymphocytes, and lymphocytosis. Conclusion: Thrombocytopenia is this most common haematological change followed by increased haematocrit, leucopenia, neutropenia and presence of atypical lymphocytes in dengue fever.

Dengue is an emerging tropical viral infection caused by an ssRNA virus of the flaviviridae family and transmitted by the bite of Aedes aegypti and Aedes albopticus mosquitoes." WHO estimates 50-100 million cases of dengue each year. More than three hundred thousand cases of dengue hemorrhagic fever (DHF) are diagnosed cach year resulting in 24,000 deaths per year’. Dengue is a self-limiting infection which causes a spectrum of illness ranging from no symptoms to life threatening DHF/dengue shock syndrome. It shares some symptoms with others infectious diseases, most of which go undiagnosed and under reported”. It is a major cause of morbidity and mortality in tropical and subtropical regions comprising more than 100 countries. Two fifths of the world’s population or 2500 million people are now at risk for dengue. The global prevalence of dengue infection has increased dramatically in the recent decades, particularly in the Americans, Western Pacific and South-East Asian regions. Early diagnosis and aggressive fluid replacement therapy with good nursing care can reduce the fatality rates to 1% or less. Serological testing is currently the standard diagnostic practice for confirmation of dengue infection.>®