TMSS Medical College Journal

Angiomyofibroblastoma(AMFB) is a rare benign mesenchymal tumor that predominantly affects the vulvovaginal region, commonly diagnosed in middle-aged women. Histopathological and immunohistochemical evaluations remain essential for accurate diagnosis. AMFB typically exhibits slow growth and a low recurrence rate after complete surgical excision. We report a case of vulvar AMFB in a 23-year-old woman, highlighting the diagnostic challenges associated with this uncommon tumor.

Angiomyofibroblastoma is a benign mesenchymal tumor that predominantly affects the vulvovaginal region in a woman, particularly those in their reproductive years." It has been reported as a rare tumor, with limited incidence and data available emphasizing its uncommon nature. It frequently develops in the vulva, though it can be found in the perineum and vagina? The first case series of this tumor was published by Fletcher et al. in 1992. Clinically, angiomyofibroblastoma presents as a painless, slow growing mass, which can be mistaken for other benign conditions like Bartholin’s cyst, lipoma, hemangioma, fibroma, leiomyoma.* This case report discusses a 23-year-old woman with pedunculated vulvar lump, surgically excised and diagnosed as AMFB, underscoring the importance of considering AMFB in the differential diagnosis of vulvar masses.