Tuberculosis is a major public health problem worldwide. Urogenital tuberculosis is the 3rd most common manifestation of extrapulmonary tuberculosis. Endometrial tuberculosis is a rare form of genital tuberculosis infection. The diagnosis is not straightforward due to the nature of its presentation. We report a case of endometrial TB in a young, healthy and immunocompetent patient, who presented to us with primary infertility.

Infertility, Tuberculosis, Amenorrhea

Tuberculosis (TB) is a major public health problem worldwide. Despite a declining trend in mortality, with effective diagnosis and treatment, An estimated 10-6 million people became ill with tuberculosis in 2021, compared with 10-1 million in 2020." Tuberculous infection of the female genital organs can result in infertility, dyspareunia, menstrual irregularities and chronic pelvic inflammatory disease.” However, the burden of genital TB in females is underestimated as most of the patients are asymptomatic and usually diagnosed during evaluation for infertility.’ Genital TB in females is well recognized as an important etiological factor for infertility in countries with high prevalence of TB. Genital TB usually occurs secondary to TB in other sites primarily, the lungs from where spreads to the genital organs by hematogenous or lymphatic routs.’ Drug therapy for female genital TB is similar to the standard treatment regimens used for pulmonary TB. Here we present a case of endometrial tuberculosis causing secondary amenorrhea with primary infertility.