TMSS Medical College Journal

Introduction: COVID-19 pandemic or also known as corona virus pandemic is an ongoing pandemic of corona virus disease 2019 caused by SARS-CoV-2 is now a major concern for the world. It became a pandemic all over the world in only 3 months and now a cause of many deaths and disabilities. This study was conducted to better understand the clinical and laboratory characteristics of the dead patients due to COVID-19. Materials and Methods: Total 45 patients with confirmed SARS coV-2 have been chosen all of whom had died during admission to COVID-19 ward or COVID-19 ICU of TMSS Medical College and Rafatullah Community Hospital, Bogura for this retrospective study. Their socio-demographic data, clinical characteristics, morbidities, laboratory as well as CT scan results were analyzed & compared. Results: Among 45 deaths most were male. Most of them had at least one comorbidity, among them DM and HTN were most common. All the patients had increased levels of CRP and D-dimer on biochemical investigations. Of those who’s CT scan of chest could be done, most had bilateral lung involvement with ground glass opacities most commonly affecting lower lobes. Acute respiratory failure was the most common cause of death followed by cardiovascular events. Conclusion: The common risk factors for COVID-19 deaths were male gender, presence of comorbidities like DM, HTN, CKD etc. Most of the dead patients had very severe symptoms on admission and died due to respiratory failure. These findings are consistent with other studies and more studies should be done to better understand the disease.

The COVID-19 pandemic, also known as the corona virus pandemic, is an ongoing pandemic of corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), first identified in December 2019 in Wuhan, China. The World Health Organization declared the outbreak a Public Health Emergency of International Concern in January 2020 and a pandemic in March 2020." The outbreak spread from the Chinese city of Wuhan to more than 180 countries and territories—affecting every continent except Antarctica.” Globally, the deaths-to-infections ratio stood at about 6.9 percent by April 22, with 175,694 deaths and over 2.54 million confirmed cases worldwide, according to WHO data. That means about 6.9 percent of people known to be infected with the corona virus have died worldwide’ As of 18 November 2020, more than 55.6 million cases have been confirmed, with more than 1.34 million deaths attributed to COVID-19.* Different virus epidemics take place throughout the world every year, but only a few rises to the level of public concern.’ Severe acute respiratory syndrome (SARS), swine influenza A HINI virus (HIN), and Zaire Ebola virus (Ebola) brought on the public's attention because they caused many severe infections and thousands of deaths.’