Profile analysis of COVID-19 suspected person attending for Real Time-PCR (RT-PCR) test in a tertiary level hospital, Bogura, Bangladesh
Abstract
Background: On 11th March, 2020 COVIDI19 was declared as a pandemic by WHO for its rapid spreading and it
currently involves more than 210 countries worldwide. only to diagnose the disease (confirm case) but also to control and
contain the transmission; test, trace and isolation are fundamental. Bangladesh declared its first case on 8th March 2020.
RT-PCR for SARS-CoV-2 is used to detect and diagnose COVID-19 which started in TMSS Medical College and
Rafatullah Community Hospital (TMC & RCH) on 1* May 2020. In this study, the profile of the COVID-19 suspects has
been analyzed attended for RT-PCR Test in TMC & RCH, Bogura, Bangladesh. Materials and Methods: This
cross-sectional descriptive study was done to find out the rate of RT-PCR positivity in suspected COVID-19 suspected
attending in TMC & RCH from 1* May to 30 June, 2020. Data was collected from the ‘sample collection form’ and the
‘registry book” of the department of Microbiology. The total number of respondents was 3120. Both the univariate and
bivariate statistics were used to analyzed the data through IBM SPSS 25.0 software. Results: Demographic data, travel
history, clinical features, and outcomes were summarized and compared with the results of RT-PCR test for
SARS-CoV-2. Among the total studied population (n=3120), 76.3% (n=2379) were male with a mean age of 40.9 (+14.8)
years. 38.8% (n=1212) were service holders (non-medical) and 61.2% were from the urban area. RT-PCR test for
SARS-CoV-2 was positive among 36.7% (n=1144). Mean age was higher among the SARS-CoV-2 positive (43.5+ 14.7
years vs 39.43+14.61 years). The number of service holders and businessmen were also higher among the positive patients
and which is statistically significant (p<0.000). Conclusion: High rate of positivity of RT-PCR for SARS-CoV-2 among
the suspected population for COVID-19 indicated high disease burden and transmission in this highly populated area in
the early period of pandemic which should be considered as was alarming.
Keywords
COVID-19; RT-PCR; SARS-CoV-2; TMC & RCH
Introduction
The outbreak of novel coronavirus-2 (nCoV-2) was declared as a pandemic and an international public health emergency by the World Health organization (WHO) on March 2020. The whole world comprehensively is working to address this pandemic due to rapidly its spreading and emerging situation. After appearing of this virus in December 2019, it has been currently (June 10, 2020) identified in 213 countries and territories across the world, by which more than 7 million people has listed as confirmed cases novel coronavirus positive. Although about 3.61 million of patients have already recovered, and another 0.4 million patients have been reported as death globally'. To understand the biology of nCoV-2 and the epidemiology of the novel coronavirus disease known as (COVID-19), the number of the researchers and scholarly people around the world are desperately working together as public health emergency.